Understanding mitochondrial disease and goals for its treatment.

Abstract excerpt

Mitochondrial disease is a progressive, debilitating, incurable illness that results from mutation of genes that regulate mitochondrial function. The disease can manifest in utero or at birth, during childhood, or have a delayed onset in adulthood. Mitochondrial disease can be transmitted as a genetically carried mutation or develop as a spontaneous genetic mutation later in life. As a multisystem disease with a...

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