Article
Host genetic factors in susceptibility to mycobacterial disease.
Clinical medicine (London, England) - 1 Dec 2014
Duncan Christopher J A, Hambleton Sophie
Abstract excerpt
Primary immunodeficiencies (PID) are a group of rare inherited disorders that manifest as heightened susceptibility to infection, autoimmunity and/or malignancy. By exploring their genetic and cellular aetiology, we can learn much about the basis of pathogen-specific immunity in humans. This is exemplified by mycobacterial susceptibility, which occurs across several types of PID, either as an isolated problem or...
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