Article
Modulation of microRNAs in two genetically disparate chicken lines showing different necrotic enteritis disease susceptibility.
Veterinary immunology and immunopathology - 15 May 2014
Dinh Hue, Hong Yeong Ho, Lillehoj Hyun S
Abstract excerpt
MicroRNAs (miRNA) play a critical role in post-transcriptional regulation by influencing the 3'-UTR of target genes. Using two inbred White Leghorn chicken lines, line 6.3 and line 7.2 showing Marek's disease-resistant and -susceptible phenotypes, respectively, we used small RNA high-throughput sequencing (HTS) to investigate whether miRNAs are differently expressed in these two chicken lines after inducing...
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