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Article

RNA sequencing analysis in chicken spleen infected with Newcastle disease virus reveals genotype-specific immune response.

BMC genomics - 13 Nov 2025

Berihulay Haile, Luo Wei, Lin Chuxiao, Lao Ainong, Jebessa Endashaw, Zou Xian, Ji Jian, Qu Hao, Cai Manshan, Shu Dingming, Luo Chenglong

Abstract excerpt

BACKGROUND: Globally, the Newcastle disease virus (NDV) is a seriously important pathogen and results in substantial economic losses in the poultry industry. To mitigate this pathogen, the poultry industry has employed intensive breeding programs aimed at selecting genetic Lines that promote resistance and enhance immune response. Resistance to infection occurs at multiple levels and involves genotype-specific...

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Source

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Identifiers

PMID: 41233763
DOI: 10.1186/s12864-025-12078-8
PMCID: PMC12613709

Genes

CCN3
MR1
MYH3
NMU
USH1C

Provenance

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