Article
Genetic exchange of fimbrial alleles exemplifies the adaptive virulence strategy of Porphyromonas gingivalis.
PloS one - 1 Jan 2014
Kerr Jennifer E, Abramian Jared R, Dao Doan-Hieu V, Rigney Todd W, Fritz Jamie, Pham Tan, Gay Isabel, Parthasarathy Kavitha, Wang Bing-yan, Zhang Wenjian, Tribble Gena D
Abstract excerpt
Porphyromonas gingivalis is a gram-negative anaerobic bacterium, a member of the human oral microbiome, and a proposed "keystone" pathogen in the development of chronic periodontitis, an inflammatory disease of the gingiva. P. gingivalis is a genetically diverse species, and is able to exchange chromosomal DNA between strains by natural competence and conjugation. In this study, we investigate the role of...
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