Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hydrodynamic delivery of Cre protein to lineage-mark or time-stamp mouse hepatocytes in situ.

PloS one - 1 Jan 2014

Sonsteng Katherine M, Prigge Justin R, Talago Emily A, June Ronald K, Schmidt Edward E

Abstract excerpt

Cre-responsive fluorescent marker alleles are powerful tools for cell lineage tracing in mice; however their utility is limited by regulation of Cre activity. When targeting hepatocytes, hydrodynamic delivery of a Cre-expression plasmid can convert Cre-responsive alleles without inducing the intracellular or systemic antiviral responses often associated with viral-derived Cre-expression vectors. In this method,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Lineage
Share to Crosses, Genetic
Share to Fluorescent Dyes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Green Fluorescent Proteins

Share to Hepatocytes

Share to Integrases

Share to tat Gene Products, Human Immunodeficiency Virus

Source

Open in PubMed Open full text

Identifiers

PMID: 24626158
DOI: 10.1371/journal.pone.0091219
PMCID: PMC3953374

Genes

TAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hydrodynamic delivery of Cre protein to lineage-mark or time-stamp mouse hepatocytes in situ.PMID 24626158Read ↗

Cre‐ativity in the liver: Transgenic approaches to targeting hepatic nonparenchymal cellsSemantic proximity Read ↗

Hydrodynamic Transfection for Generation of Novel Mouse Models for Liver Cancer ResearchSemantic proximity Read ↗

Specificity and off-target effects of AAV8-TBG viral vectors for the manipulation of hepatocellular gene expression in miceSemantic proximity Read ↗

Hydrodynamic delivery of DNASemantic proximity Read ↗

Efficient Gene Delivery and Targeted Expression to Hepatocytes <i>In Vivo</i> by Improved Lentiviral VectorsSemantic proximity Read ↗

A mouse reporter line to conditionally mark nuclei and cell membranes for in vivo live-imaging.Semantic proximity Read ↗

Analysis of primitive erythroid cell proliferation and enucleation using a cyan fluorescent reporter in transgenic mice.Semantic proximity Read ↗

Temporally and spatially controlled expression of transgenes in embryonic and adult tissues.Semantic proximity Read ↗

Albumin gene targeting in human embryonic stem cells and induced pluripotent stem cells with helper-dependent adenoviral vector to monitor hepatic differentiationSemantic proximity Read ↗

Lineage-specific cell disruption in living mice by Cre-mediated expression of diphtheria toxin A chainSemantic proximity Read ↗

MRI reporter genes: applications for imaging of cell survival, proliferation, migration and differentiationSemantic proximity Read ↗

Generation of H11-albumin-rtTA Transgenic Mice: A Tool for Inducible Gene Expression in the LiverSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.