Article
Candida albicans uses the surface protein Gpm1 to attach to human endothelial cells and to keratinocytes via the adhesive protein vitronectin.
PloS one - 1 Jan 2014
Lopez Crisanto M, Wallich Reinhard, Riesbeck Kristian, Skerka Christine, Zipfel Peter F
Abstract excerpt
Candida albicans is a major cause of invasive fungal infections worldwide. Upon infection and when in contact with human plasma as well as body fluids the fungus is challenged by the activated complement system a central part of the human innate immune response. C. albicans controls and evades host complement attack by binding several human complement regulators like Factor H, Factor H-like protein 1 and C4BP to...
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