Article
Inhibition of HSP70 reduces porcine reproductive and respiratory syndrome virus replication in vitro
13 Mar 2014
Abstract excerpt
BACKGROUND: Successful viral infection requires the involvement of host cellular factors in their life cycle. Heat shock protein 70 (HSP70) can be recruited by numerous viruses to promote the folding, maturation, or assembly of viral proteins. We have previously shown that HSP70 is significantly elevated in porcine reproductive and respiratory syndrome virus (PRRSV)-infected lungs, suggesting HSP70 may play a...
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