Article
A novel function of the Fe65 neuronal adaptor in estrogen receptor action in breast cancer cells.
The Journal of biological chemistry - 2 May 2014
Sun Yuefeng, Kasiappan Ravi, Tang Jinfu, Webb Panida L, Quarni Waise, Zhang Xiaohong, Bai Wenlong
Abstract excerpt
Fe65 is a multidomain adaptor with established functions in neuronal cells and neurodegeneration diseases. It binds to the C terminus of the Aβ amyloid precursor protein and is involved in regulating gene transcription. The present studies show that Fe65 is expressed in breast cancer (BCa) cells...
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