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Article

Clinical flow cytometric screening of SAP and XIAP expression accurately identifies patients with SH2D1A and XIAP/BIRC4 mutations.

Cytometry. Part B, Clinical cytometry - 1 Jul 2014

Gifford Carrie E, Weingartner Elizabeth, Villanueva Joyce, Johnson Judith, Zhang Kejian, Filipovich Alexandra H, Bleesing Jack J, Marsh Rebecca A

Abstract excerpt

INTRODUCTION: X-linked lymphoproliferative disease is caused by mutations in two genes, SH2D1A and XIAP/BIRC4. Flow cytometric methods have been developed to detect the gene products, SAP and XIAP. However, there is no literature describing the accuracy of flow cytometric screening performed in a clinical lab setting. METHODS: We reviewed the clinical flow cytometric testing results for 656 SAP and 586 XIAP...

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Identifiers

PMID: 24616127
DOI: 10.1002/cyto.b.21166

Genes

XIAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Clinical flow cytometric screening of SAP and XIAP expression accurately identifies patients with SH2D1A and XIAP/BIRC4 mutations.PMID 24616127Read ↗

Clinical Flow Cytometric Screening of SAP and XIAP Expression Accurately Identifies Patients with<i>SH2D1A</i>and<i>XIAP/BIRC4</i>MutationsSemantic proximity Read ↗

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