Article
Association of IRS1, CAPN10, and PPARG gene polymorphisms with type 2 diabetes mellitus in the high-risk population of Hyderabad, India.
Journal of diabetes - 1 Nov 2014
Kommoju Uma Jyothi, Maruda Jayaraj, Kadarkarai Samy Subburaj, Irgam Kumuda, Kotla Jaya Prasad, Reddy Battini Mohan
Abstract excerpt
BACKGROUND: We attempted to validate earlier findings on the nature of the association of the IRS1, CAPN10, and PPARG genes with type 2 diabetes mellitus (T2DM) in the high-risk population of Hyderabad, India. METHODS: A sample of 1379 subjects (758 T2DM patients, 621 controls) was genotyped for single nucleotide polymorphisms (SNPs) of the IRS1 (rs1801278), CAPN10 (rs3792267, rs5030952), and PPARG (rs1801282)...
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