Article
Aeroallergen sensitization in asthma: genetics, environment, and pathophysiology.
Allergy and asthma proceedings - 1 Jan 2000
Long Aidan
Abstract excerpt
A complex interplay of genetic predisposition and environmental influences results in the clinical picture of allergic asthma. This article addresses recently identified genetic markers and environmental factors that contribute to disease development in asthma. Focus is placed on aspects of the innate immune system, including inherent properties of allergens, the active role of airway epithelium, and the central...
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