Article
Associations of VEGF-C genetic polymorphisms with urothelial cell carcinoma susceptibility differ between smokers and non-smokers in Taiwan.
PloS one - 1 Jan 2014
Tung Min-Che, Hsieh Ming-Ju, Wang Shian-Shiang, Yang Shun-Fa, Chen Shiou-Sheng, Wang Shih-Wei, Lee Liang-Ming, Lee Wei-Jiunn, Chien Ming-Hsien
Abstract excerpt
BACKGROUND: Vascular endothelial growth factor (VEGF)-C is associated with lymphangiogenesis, pelvic regional lymph node metastasis, and an antiapoptotic phenotype in urothelial cell carcinoma (UCC). Knowledge of potential roles of VEGF-C genetic polymorphisms in susceptibility to UCC is lacking. This study was designed to examine associations between VEGF-C gene variants and UCC susceptibility and evaluate...
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