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Activin A supplement in the hESCs culture enhances the endoderm differentiation efficiency

7 Mar 2014

Abstract excerpt

Activin A is a critical regulator in human embryonic stem cells (hESCs) maintenance and differentiation. Different concentrations of Activin A affect hESC maintenance and differentiation in different ways. A high concentration favors anterior primitive streak and gives rise to DE if the stimulation persists. hESCs were cultured with and without 10 ng/mL Activin A supplement respectively. The two groups of cells...

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PMID: 24604611
DOI: 10.1002/cbin.10274

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