Article
Association of tardive dyskinesia with variation in CYP2D6: Is there a role for active metabolites?
Journal of psychopharmacology (Oxford, England) - 1 Jul 2014
Koola Maju M, Tsapakis Evangelia M, Wright Padraig, Smith Shubulade, Kerwin Rip Robert W, Nugent Katie L, Aitchison Katherine J
Abstract excerpt
BACKGROUND: The aim of this study was to examine whether there was an association between tardive dyskinesia (TD) and number of functional CYP2D6 genes. METHODS: A Caucasian sample of 70 patients was recruited in 1996-1997 from South London and Maudsley National Health Service (NHS) Foundation Trust, UK. Subjects had a DSM-IIIR diagnosis of schizophrenia and were treated with typical antipsychotics at doses...
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