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Article

In vivo functional analysis of the human NF2 tumor suppressor gene in Drosophila.

PloS one - 1 Jan 2014

Gavilan Heather S, Kulikauskas Rima M, Gutmann David H, Fehon Richard G

Abstract excerpt

The proper control of tissue growth is essential during normal development and an important problem in human disease. Merlin, the product of the Neurofibromatosis 2 tumor suppressor gene, has been extensively studied to understand its functions in growth control. Here we describe experiments in which we used Drosophila as an in vivo system to test the functions of the normal human NF2 gene products and...

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Identifiers

PMID: 24595234
DOI: 10.1371/journal.pone.0090853
PMCID: PMC3942481

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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