Article
How, and from which cell sources, do nevi really develop?
Experimental dermatology - 1 May 2014
Grichnik James M, Ross Andrew L, Schneider Samantha L, Sanchez Margaret I, Eller Mark S, Hatzistergos Konstantinos E
Abstract excerpt
Melanocytic neoplasms are a diverse group of benign and malignant tumors with variable clinical features. While some models still promote the epidermal melanocyte as the origin of melanocytic neoplasms, clinical findings are inconsistent with this theory for the majority of tumors. Despite advances in naevus and melanoma biology, the location and differentiation status of the cell of origin remains undefined....
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