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Article

A novel mutation in the TECTA gene in a Chinese family with autosomal dominant nonsyndromic hearing loss.

PloS one - 1 Jan 2014

Su Yu, Tang Wen-Xue, Gao Xue, Yu Fei, Dai Zhi-Yao, Zhao Jian-Dong, Lu Yu, Ji Fei, Huang Sha-Sha, Yuan Yong-Yi, Han Ming-Yu, Song Yue-Shuai, Zhu Yu-Hua, Kang Dong-Yang, Han Dong-Yi, Dai Pu

Abstract excerpt

TECTA-related deafness can be inherited as autosomal-dominant nonsyndromic deafness (designated DFNA) or as the autosomal-recessive version. The α-tectorin protein, which is encoded by the TECTA gene, is one of the major components of the tectorial membrane in the inner ear. Using targeted DNA capture and massively parallel sequencing (MPS), we screened 42 genes known to be responsible for human deafness in a...

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Identifiers

PMID: 24586623
DOI: 10.1371/journal.pone.0089240
PMCID: PMC3931719

Genes

TECTA

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Source receipt: pubmed, retrieved 7 Sept 2026.

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