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Article

Genome Scale Patterns of Recombination between Coinfecting Vaccinia Viruses

27 Feb 2014

Abstract excerpt

UNLABELLED: Recombination plays a critical role in virus evolution. It helps avoid genetic decline and creates novel phenotypes. This promotes survival, and genome sequencing suggests that recombination has facilitated the evolution of human pathogens, including orthopoxviruses such as variola virus. Recombination can also be used to map genes, but although recombinant poxviruses are easily produced in culture,...

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PMID: 24574414
DOI: 10.1128/jvi.00022-14

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