Article
High-throughput screening and whole genome sequencing identifies an antimicrobially active inhibitor of Vibrio cholerae.
BMC microbiology - 26 Feb 2014
Sergeev Galina, Roy Sambit, Jarek Michael, Zapolskii Viktor, Kaufmann Dieter E, Nandy Ranjan K, Tegge Werner
Abstract excerpt
BACKGROUND: Pathogenic serotypes of Vibrio cholerae cause the life-threatening diarrheal disease cholera. The increasing development of bacterial resistances against the known antibiotics necessitates the search for new antimicrobial compounds and targets for this pathogen. RESULTS: A high-throughput screening assay with a Vibrio cholerae reporter strain constitutively expressing green fluorescent protein (GFP)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
