Article
Evolution and circulation of type-2 vaccine-derived polioviruses in Nad Ali district of Southern Afghanistan during June 2009-February 2011.
PloS one - 1 Jan 2014
Sharif Salmaan, Abbasi Bilal Haider, Khurshid Adnan, Alam Muhammad Masroor, Shaukat Shahzad, Angez Mehar, Rana Muhammad Suleman, Zaidi Syed Sohail Zahoor
Abstract excerpt
Oral polio vaccine has been used successfully as a powerful tool to control the spread of wild polioviruses throughout the world; however, during replication in under immunized children, some vaccine viruses revert and acquire the neurovirulent phenotypic properties. In this study, we describe the evolution and circulation of Vaccine-Derived Polioviruses (VDPVs) in Helmand province of Afghanistan. We investigated...
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