Article
Linking toxicity and adaptive responses across the transcriptome, proteome, and phenotype of Chlamydomonas reinhardtii exposed to silver.
Proceedings of the National Academy of Sciences of the United States of America - 4 Mar 2014
Pillai Smitha, Behra Renata, Nestler Holger, Suter Marc J-F, Sigg Laura, Schirmer Kristin
Abstract excerpt
Understanding mechanistic and cellular events underlying a toxicological outcome allows the prediction of impact of environmental stressors to organisms living in different habitats. A systems-based approach aids in characterizing molecular events, and thereby the cellular pathways that have been perturbed. However, mapping only adverse outcomes of a toxicant falls short of describing the stress or adaptive...
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