Lack of associations between genetic polymorphisms in GSTM1, GSTT1 and GSTP1 and pancreatic cancer risk: a multi-institutional case-control study in Japan.

doi:10.7314/apjcp.2014.15.1.391

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Article

Lack of associations between genetic polymorphisms in GSTM1, GSTT1 and GSTP1 and pancreatic cancer risk: a multi-institutional case-control study in Japan.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014

Yamada Ikuhiro, Matsuyama Masato, Ozaka Masato, Inoue Dai, Muramatsu Yusuke, Ishii Hiroshi, Junko Ueda, Ueno Makoto, Egawa Naoto, Nakao Haruhisa, Mori Mitsuru, Matsuo Keitaro, Nishiyama Takeshi, Ohkawa Shinichi, Hosono Satoyo, Wakai Kenji, Nakamura Kozue, Tamakoshi Akiko, Kuruma Sawako, Nojima Masanori, Takahashi Mami, Shimada Kazuaki, Yagyu Kiyoko, Kikuchi Shogo, Lin Yingsong

Abstract excerpt

BACKGROUND: We aimed to evaluate the role of genetic polymorphisms in tobacco carcinogen-metabolizing genes and their interactions with smoking in a hospital-based case-control study of Japanese subjects. MATERIALS AND METHODS: We examine the associations of pancreatic cancer risk with genetic polymorphisms in GSTM1, GSTT1 and GSTP1, phase II enzymes that catalyze the conjugation of toxic and carcinogenic...

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Identifiers

PMID: 24528063
DOI: 10.7314/apjcp.2014.15.1.391

Genes

GSTM1
GSTT1
GSTP1

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