Article
Fcγ receptor-mediated inflammation inhibits axon regeneration.
PloS one - 1 Jan 2014
Zhang Gang, Bogdanova Nataliia, Gao Tong, Song Julia J, Cragg Mark S, Glennie Martin J, Sheikh Kazim A
Abstract excerpt
Anti-glycan/ganglioside antibodies are the most common immune effectors found in patients with Guillain-Barré Syndrome, which is a peripheral autoimmune neuropathy. We previously reported that disease-relevant anti-glycan autoantibodies inhibited axon regeneration, which echo the clinical association of these antibodies and poor recovery in Guillain-Barré Syndrome. However, the specific molecular and cellular...
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