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Article

Role of fatty acid synthase in the development of Dictyostelium discoideum.

Journal of oleo science - 1 Jan 2014

Narita Takaaki B, Kikukawa Takahiro W, Sato Yukie G, Miyazaki Saki H, Morita Naoki, Saito Tamao

Abstract excerpt

Fatty acids are fundamental cellular components, and provide essential building blocks for membrane biosynthesis. Although the use of gene knockout mutants is a robust method for examining the function of specific cellular metabolic networks, fatty acid synthase knockout mutants are extremely difficult to isolate. In the Dictyostelium discoideum genome, we found two putative fatty acid synthase genes, and we...

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PMID: 24521843
DOI: 10.5650/jos.ess13142

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