Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic diversity of PCR-positive, culture-negative and culture-positive Mycobacterium ulcerans isolated from Buruli ulcer patients in Ghana.

PloS one - 1 Jan 2014

Williamson Heather, Phillips Richard, Sarfo Stephen, Wansbrough-Jones Mark, Small Pamela

Abstract excerpt

Culture of Mycobacterium ulcerans from Buruli ulcer patients has very low sensitivity. Thus confirmation of M. ulcerans infection is primarily based on PCR directed against IS2404. In this study we compare the genotypes obtained by variable number of tandem repeat analysis of DNA from IS2404-PCR positive cultures with that obtained from IS2404 positive, culture-negative tissue. A significantly greater genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biopsy
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Minisatellite Repeats

Share to Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 24520343
DOI: 10.1371/journal.pone.0088007
PMCID: PMC3919753

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic diversity of PCR-positive, culture-negative and culture-positive Mycobacterium ulcerans isolated from Buruli ulcer patients in Ghana.PMID 24520343Read ↗

PCR amplification with primers based on IS2404 and GC-rich repeated sequence reveals polymorphism in Mycobacterium ulcerans.Semantic proximity Read ↗

Whole genome comparisons suggest random distribution of Mycobacterium ulcerans genotypes in a Buruli ulcer endemic region of Ghana.Semantic proximity Read ↗

Single nucleotide polymorphism typing of Mycobacterium ulcerans reveals focal transmission of buruli ulcer in a highly endemic region of Ghana.Semantic proximity Read ↗

Heterogeneity among Mycobacterium ulcerans isolates from Africa.Semantic proximity Read ↗

The use of IS2404 restriction fragment length polymorphisms suggests the diversity of Mycobacterium ulcerans from different geographical areas.Semantic proximity Read ↗

A simple PCR method for rapid genotype analysis of Mycobacterium ulcerans.Semantic proximity Read ↗

Genomic diversity and evolution of Mycobacterium ulcerans revealed by next-generation sequencing.Semantic proximity Read ↗

Genetic diversity in Mycobacterium ulcerans isolates from Ghana revealed by a newly identified locus containing a variable number of tandem repeats.Semantic proximity Read ↗

Variability in 3' end of 16S rRNA sequence of Mycobacterium ulcerans is related to geographic origin of isolates.Semantic proximity Read ↗

Multilocus VNTR analysis of Mycobacterium ulcerans strains isolated in Côte d'Ivoire.Semantic proximity Read ↗

Comparative nucleotide sequence analysis of polymorphic variable-number tandem-repeat Loci in Mycobacterium ulcerans.Semantic proximity Read ↗

Analysis of an IS<i>2404</i>-Based Nested PCR for Diagnosis of Buruli Ulcer Disease in Regions of Ghana Where the Disease Is EndemicSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.