Article
Clinical characteristics of patients with KRAS mutation detected by liquid biopsy.
Thoracic cancer - 1 Nov 2023
Amino Yoshiaki, Low Siew-Kee, Ninomiya Hironori, Kiritani Ayu, Miyadera Keiki, Kakuto Sho, Akita Takahiro, Tsugitomi Ryosuke, Ariyasu Ryo, Uchibori Ken, Kitazono Satoru, Yanagitani Noriko, Nishio Makoto
Abstract excerpt
BACKGROUND: KRAS mutation positive lung cancer is known to be clinically characterized by older age, males, and smokers. It is reported to be more common in mucinous adenocarcinoma, but all reports are based on analysis of tissue samples. Recently, blood samples have become available for analysis, suggesting a low detection rate of circulating tumor DNA in histological types, especially mucinous adenocarcinoma....
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