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Article

Critical role of microRNA-155 in herpes simplex encephalitis.

Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 2014

Bhela Siddheshvar, Mulik Sachin, Reddy Pradeep B J, Richardson Raphael L, Gimenez Fernanda, Rajasagi Naveen K, Veiga-Parga Tamara, Osmand Alexander P, Rouse Barry T

Abstract excerpt

HSV infection of adult humans occasionally results in life-threatening herpes simplex encephalitis (HSE) for reasons that remain to be defined. An animal system that could prove useful to model HSE could be microRNA-155 knockout (miR-155KO) mice. Thus, we observe that mice with a deficiency of miR-155 are highly susceptible to HSE with a majority of animals (75-80%) experiencing development of HSE after ocular...

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Identifiers

PMID: 24516198
DOI: 10.4049/jimmunol.1302326
PMCID: PMC3951608

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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