Article
Genetic alterations and personalized medicine in melanoma: progress and future prospects.
Journal of the National Cancer Institute - 1 Feb 2014
Griewank Klaus G, Scolyer Richard A, Thompson John F, Flaherty Keith T, Schadendorf Dirk, Murali Rajmohan
Abstract excerpt
High-throughput sequencing technologies are providing new insights into the genetic alterations involved in melanomagenesis. It appears likely that most genetic events important in the pathogenesis of melanoma will be discovered over the next few years. Genetic analysis is also increasingly being used to direct patient care. In parallel with the discovery of new genes and the elucidation of molecular pathways...
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