Toward a molecular classification of melanoma.

doi:10.1200/JCO.2006.06.0442

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Article

Toward a molecular classification of melanoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Apr 2007

Fecher Leslie A, Cummings Staci D, Keefe Megan J, Alani Rhoda M

Abstract excerpt

The incidence of melanoma is increasing at one of the highest rates of any form of cancer in the United States, with the current lifetime risk being one in 68. At present, there are limited systemic therapies to treat advanced stages of melanoma, and the key to improved survival remains early detection. Recent discoveries have allowed for a clearer picture of the molecular events leading to melanoma development...

Topics

Female
Gene Expression Regulation, Neoplastic
Genes, Tumor Suppressor
Genes, ras
Genetic Predisposition to Disease
Germ-Line Mutation
Humans
Incidence
Male
Melanoma
Mitogen-Activated Protein Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Biology

Proto-Oncogene Proteins B-raf

Receptor, Melanocortin, Type 1

Sensitivity and Specificity

Skin Neoplasms

Survival Analysis

Source

Open in PubMed

Identifiers

PMID: 17443002
DOI: 10.1200/JCO.2006.06.0442

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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