Article
[Association study of bronchial asthma with polymorphisms of IL-4 and IL-4R receptor genes].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Feb 2014
Liang Wenhua, Zhou Zhaoshan, Ji Zhongqiang, Wang Yanqing, Xue Weilin, Zhang Xiaoyan
Abstract excerpt
OBJECTIVE: To assess the association of polymorphisms of IL-4 gene (rs2243250, rs2243283) and IL-4R gene (rs1805012, rs1801275, rs1805010) with susceptibility to asthma among ethnic Chinese in Qingdao. METHODS: For 400 asthma patients and 200 healthy subjects, above polymorphisms were detected with SnaPshot method. RESULTS: For , the frequency of TC genotype in the asthma group was significantly lower...