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Article

Vectored immunoprophylaxis protects humanized mice from mucosal HIV transmission.

Nature medicine - 1 Mar 2014

Balazs Alejandro B, Ouyang Yong, Hong Christin M, Chen Joyce, Nguyen Steven M, Rao Dinesh S, An Dong Sung, Baltimore David

Abstract excerpt

The vast majority of new HIV infections result from relatively inefficient transmission of the virus across mucosal surfaces during sexual intercourse. A consequence of this inefficiency is that small numbers of transmitted founder viruses initiate most heterosexual infections. This natural bottl...

Read the complete abstract on PubMed

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Share to Receptors, CCR5
Share to Antibodies, Neutralizing
Share to CD4-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dependovirus

Share to env Gene Products, Human Immunodeficiency Virus

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Share to Leukocytes, Mononuclear

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Source

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Identifiers

PMID: 24509526
DOI: 10.1038/nm.3471
PMCID: PMC3990417

Genes

VIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24509526-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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