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Article

Mouse early extra-embryonic lineages activate compensatory endocytosis in response to poor maternal nutrition

7 Feb 2014

Abstract excerpt

Mammalian extra-embryonic lineages perform the crucial role of nutrient provision during gestation to support embryonic and fetal growth. These lineages derive from outer trophectoderm (TE) and internal primitive endoderm (PE) in the blastocyst and subsequently give rise to chorio-allantoic and visceral yolk sac placentae, respectively. We have shown maternal low protein diet exclusively during mouse...

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PMID: 24504338
DOI: 10.1242/dev.103952

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