Article
Telomere length of recipients and living kidney donors and chronic graft dysfunction in kidney transplants.
Transplantation - 15 Feb 2014
Oetting William S, Guan Weihua, Schladt David P, Wildebush Winston A, Becker Jennifer, Thyagarajan Bharat, Jacobson Pamala A, Matas Arthur J, Israni Ajay K
Abstract excerpt
BACKGROUND: A biological marker that would allow clinicians to determine the length of time an allograft will remain functional after transplantation would greatly aid the ability to stratify donors by risk and to use biologically "young" allografts in young recipients, maximizing the use of this rare resource. Telomere length (TL) has been proposed to be such a marker to determine the biological age of a tissue....
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