Article
Gut microbiome phenotypes driven by host genetics affect arsenic metabolism.
Chemical research in toxicology - 17 Feb 2014
Lu Kun, Mahbub Ridwan, Cable Peter Hans, Ru Hongyu, Parry Nicola M A, Bodnar Wanda M, Wishnok John S, Styblo Miroslav, Swenberg James A, Fox James G, Tannenbaum Steven R
Abstract excerpt
Large individual differences in susceptibility to arsenic-induced diseases are well-documented and frequently associated with different patterns of arsenic metabolism. In this context, the role of the gut microbiome in directly metabolizing arsenic and triggering systemic responses in diverse organs raises the possibility that gut microbiome phenotypes affect the spectrum of metabolized arsenic species. However,...
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