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Article

Generation of disease-specific induced pluripotent stem cells from patients with rheumatoid arthritis and osteoarthritis

4 Feb 2014

Abstract excerpt

INTRODUCTION: Since the concept of reprogramming mature somatic cells to generate induced pluripotent stem cells (iPSCs) was demonstrated in 2006, iPSCs have become a potential substitute for embryonic stem cells (ESCs) given their pluripotency and "stemness" characteristics, which resemble those of ESCs. We investigated to reprogram fibroblast-like synoviocytes (FLSs) from patients with rheumatoid arthritis (RA)...

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PMID: 24490617
DOI: 10.1186/ar4470

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