Article
Poly (glycerol sebacate) elastomer supports osteogenic phenotype for bone engineering applications.
Biomedical materials (Bristol, England) - 1 Apr 2014
Zaky Samer H, Hangadora Catherine K, Tudares Mauro A, Gao Jin, Jensen Adrianna, Wang Yadong, Sfeir Charles, Almarza Alejandro J
Abstract excerpt
For bone engineering, the optimal scaffolding material and composition has yet to be elucidated. In this study, we investigated poly (glycerol sebacate) (PGS), an elastomer known primarily for its soft tissue regeneration ability, as a suitable substrate to support osteo-precursor cell attachment and function. We synthesized PGS in the form of sheets where MC3T3-E1 cells were seeded in three different densities...
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