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Article

Cerebral metabolic abnormalities in A3243G mitochondrial DNA mutation carriers.

Neurology - 4 Mar 2014

Weiduschat Nora, Kaufmann Petra, Mao Xiangling, Engelstad Kristin Marie, Hinton Veronica, DiMauro Salvatore, De Vivo Darryl, Shungu Dikoma

Abstract excerpt

OBJECTIVE: To establish cerebral metabolic features associated with the A3243G mitochondrial DNA mutation with proton magnetic resonance spectroscopic imaging ((1)H MRSI) and to assess their potential as prognostic biomarkers. METHODS: In this prospective cohort study, we investigated 135 clinically heterogeneous A3243G mutation carriers and 30 healthy volunteers (HVs) with (1)H MRSI. Mutation carriers included...

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Identifiers

PMID: 24477106
DOI: 10.1212/WNL.0000000000000169
PMCID: PMC3945652

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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