Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dynamic expression of molecules that control limb muscle development including Fhl1 in hind limbs of different gestational age.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Sept 2014

Wang Li-Li, Peng Zhao-Hong, Fan Yang, Li Lian-Yong, Wu Di, Zhang Yi, Miao Jia-Ning, Bai Yu-Zuo, Yuan Zheng-Wei, Wang Wei-Lin, Sun Kai-Lai

Abstract excerpt

Muscle abnormality could be a key reason for congenital clubfoot (CCF) deformity, which manifests itself during fetal development. FHL1 down-regulated expression is involved in the formation of skeletal muscle abnormalities in CCF and FHL1 gene mutations contribute to the development of some kinds of myopathies. Therefore, detecting dynamic expression of Fhl1 and other molecules (Hgf, MyoD1, Myogenin, and Myh4)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clubfoot
Share to Hepatocyte Growth Factor

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hindlimb

Share to LIM Domain Proteins

Share to Muscle Development

Share to Muscle Fibers, Skeletal

Share to MyoD Protein

Share to Myogenin

Source

Identifiers

PMID: 24475781
DOI: 10.1111/apm.12217

Genes

FHL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dynamic expression of molecules that control limb muscle development including Fhl1 in hind limbs of different gestational age.PMID 24475781Read ↗

Developmental myosins: expression patterns and functional significanceSemantic proximity Read ↗

Maternal smoking during pregnancy aggravated muscle phenotype in FHL1-/y offspring mice similar to congenital clubfoot through P2RX7-mediated pyroptosis.Semantic proximity Read ↗

Gene expression differences associated with intrinsic hindfoot muscle loss in the jerboa, <i>Jaculus jaculus</i>Semantic proximity Read ↗

Expression patterns of FHL/SLIM family members suggest important functional roles in skeletal muscle and cardiovascular systemSemantic proximity Read ↗

Transcriptomic profile of leg muscle during early growth in chickenSemantic proximity Read ↗

Evaluation of embryonic and perinatal myosin gene mutations and the etiology of congenital idiopathic clubfoot.Semantic proximity Read ↗

Myogenin gene disruption results in perinatal lethality because of severe muscle defect.Semantic proximity Read ↗

[HOX genes and the limb development in the clinical praxis and in the experiment].Semantic proximity Read ↗

Isolation and characterization of a new FHL1 variant (FHL1C) from porcine skeletal muscle.Semantic proximity Read ↗

FHL3 promotes the formation of fast glycolytic muscle fibers by interacting with YY1 and muscle glycolytic metabolismSemantic proximity Read ↗

Human Fast Skeletal Myosin Light Chain 2 cDNA: Isolation, Tissue Specific Expression of the Single Copy Gene, Comparative Sequence Analysis of Isoforms and Evolutionary RelationshipsSemantic proximity Read ↗

Coordination of skeletal muscle gene expression occurs late in mammalian development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.