Article
Coordination of skeletal muscle gene expression occurs late in mammalian development.
Developmental biology - 1 Jul 1991
Sutherland C J, Elsom V L, Gordon M L, Dunwoodie S L, Hardeman E C
Abstract excerpt
The acquisition of specialized skeletal muscle fiber phenotypes during development is investigated by systematic measurement of the accumulation of 21 contractile protein mRNAs during hindlimb development in the rat and the human. During early myotube formation in both species there is no coordination of expression of either fast or slow contractile protein isoform genes, but rather some slow, some fast, and some...
Topics
- Animals
- Base Sequence
- Gene Expression Regulation
- Hindlimb
- Humans
- Molecular Sequence Data
- Multigene Family
- Muscle Proteins
- Muscles
- Phenotype
- RNA, Messenger
- Rats