Article
Molecular evolution of a pervasive natural amino-acid substitution in Drosophila cryptochrome.
PloS one - 1 Jan 2014
Pegoraro Mirko, Noreen Shumaila, Bhutani Supriya, Tsolou Avgi, Schmid Ralf, Kyriacou Charalambos P, Tauber Eran
Abstract excerpt
Genetic variations in circadian clock genes may serve as molecular adaptations, allowing populations to adapt to local environments. Here, we carried out a survey of genetic variation in Drosophila cryptochrome (cry), the fly's dedicated circadian photoreceptor. An initial screen of 10 European cry alleles revealed substantial variation, including seven non-synonymous changes. The SNP frequency spectra and the...
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