Article
Genetic variations in the flanking regions of miR-101-2 are associated with increased risk of breast cancer.
PloS one - 1 Jan 2014
Chen Jiaping, Qin Zhenzhen, Jiang Yue, Wang Yanru, He Yisha, Dai Juncheng, Jin Guangfu, Ma Hongxia, Hu Zhibin, Yin Yongmei, Shen Hongbing
Abstract excerpt
Genetic variants in human microRNA (miRNA) genes may alter mature miRNA processing and/or target selection, and likely contribute to cancer susceptibility and disease progression. Previous studies have suggested that miR-101 may play important roles in the development of cancer by regulating key tumor-associated genes. However, the role of single nucleotide polymorphisms (SNPs) of miR-101 in breast cancer...
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