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Article

A novel computational biostatistics approach implies impaired dephosphorylation of growth factor receptors as associated with severity of autism.

Translational psychiatry - 28 Jan 2014

Wittkowski K M, Sonakya V, Bigio B, Tonn M K, Shic F, Ascano M, Nasca C, Gold-Von Simson G

Abstract excerpt

The prevalence of autism spectrum disorders (ASDs) has increased 20-fold over the past 50 years to >1% of US children. Although twin studies attest to a high degree of heritability, the genetic risk factors are still poorly understood. We analyzed data from two independent populations using u-statistics for genetically structured wide-locus data and added data from unrelated controls to explore epistasis. To...

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Source

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Identifiers

PMID: 24473445
DOI: 10.1038/tp.2013.124
PMCID: PMC3905234

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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