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Elucidating the Genetic Basis of Crystalline Biofilm Formation in Proteus mirabilis

28 Jan 2014

Abstract excerpt

Proteus mirabilis forms extensive crystalline biofilms on urethral catheters that occlude urine flow and frequently complicate the management of long-term-catheterized patients. Here, using random transposon mutagenesis in conjunction with in vitro models of the catheterized urinary tract, we elucidate the mechanisms underpinning the formation of crystalline biofilms by P. mirabilis. Mutants identified as...

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PMID: 24470471
DOI: 10.1128/iai.01652-13

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