Article
Genetic variants in microRNA target sites of 37 selected cancer-related genes and the risk of cervical cancer.
PloS one - 1 Jan 2014
Mi Yang, Wang Lijuan, Zong Lu, Pei Meili, Lu Qingyang, Huang Pu
Abstract excerpt
OBJECTIVES: Single nucleotide polymorphisms (SNPs) in putative microRNA binding sites (miRSNPs) modulate cancer susceptibility via affecting miRNA binding. Here, we sought to investigate the association between miRSNPs and cervical cancer risk. METHODS: We first genotyped 41 miRSNPs of 37 cancer-related genes in 338 patients and 334 controls (Study 1), and replicated the significant associations in 502 patients...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
