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Efficient Reprogramming of Naïve-Like Induced Pluripotent Stem Cells from Porcine Adipose-Derived Stem Cells with a Feeder-Independent and Serum-Free System

20 Jan 2014

Abstract excerpt

Induced pluripotent stem cells (iPSCs) are somatic cells reprogrammed by ectopic expression of transcription factors or small molecule treatment, which resemble embryonic stem cells (ESCs). They hold great promise for improving the generation of genetically modified large animals. However, few porcine iPSCs (piPSCs) lines obtained currently can support development of cloned embryos. Here, we generated iPSCs from...

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CRISPR and Genetic Engineering
Pluripotent Stem Cells Research
Tissue Engineering and Regenerative Medicine

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24465482
DOI: 10.1371/journal.pone.0085089

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