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Generation of pig induced pluripotent stem cells using an extended pluripotent stem cell culture system

27 Jun 2019

Abstract excerpt

BACKGROUND: Pigs have emerged as one of the most popular large animal models in biomedical research, which in many cases is considered as a superior choice over rodent models. In addition, transplantation studies using pig pluripotent stem (PS) cell derivatives may serve as a testbed for safety and efficacy prior to human trials. Recently, it has been shown that mouse and human PS cells cultured in LCDM...

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PMID: 31248457
DOI: 10.1186/s13287-019-1303-0

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