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Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells

8 Sept 2009

Abstract excerpt

Ectopic expression of transcription factors can reprogram somatic cells to a pluripotent state. However, most of the studies used skin fibroblasts as the starting population for reprogramming, which usually take weeks for expansion from a single biopsy. We show here that induced pluripotent stem (iPS) cells can be generated from adult human adipose stem cells (hASCs) freshly isolated from patients. Furthermore,...

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PMID: 19805220
DOI: 10.1073/pnas.0908450106

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