Article
Multibreed genome wide association can improve precision of mapping causative variants underlying milk production in dairy cattle.
BMC genomics - 24 Jan 2014
Raven Lesley-Ann, Cocks Benjamin G, Hayes Ben J
Abstract excerpt
BACKGROUND: Genome wide association studies (GWAS) in most cattle breeds result in large genomic intervals of significant associations making it difficult to identify causal mutations. This is due to the extensive, low-level linkage disequilibrium within a cattle breed. As there is less linkage disequilibrium across breeds, multibreed GWAS may improve precision of causal variant mapping. Here we test this...
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