Article
Meta-analysis for milk fat and protein percentage using imputed sequence variant genotypes in 94,321 cattle from eight cattle breeds.
Genetics, selection, evolution : GSE - 7 Jul 2020
van den Berg Irene, Xiang Ruidong, Jenko Janez, Pausch Hubert, Boussaha Mekki, Schrooten Chris, Tribout Thierry, Gjuvsland Arne B, Boichard Didier, Nordbø Øyvind, Sanchez Marie-Pierre, Goddard Mike E
Abstract excerpt
BACKGROUND: Sequence-based genome-wide association studies (GWAS) provide high statistical power to identify candidate causal mutations when a large number of individuals with both sequence variant genotypes and phenotypes is available. A meta-analysis combines summary statistics from multiple GWAS and increases the power to detect trait-associated variants without requiring access to data at the individual level...
Topics
- Animals
- Cattle
- Gene Frequency
- Genotype
- Linkage Disequilibrium
- Lipids
- Milk
- Milk Proteins
- Polymorphism, Genetic
- Quantitative Trait Loci